Cytokeratin 19 Antikörper

Produktnummer ABIN114673

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Cytokeratin 19 in WB, IF, FACS, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human und Zebrafisch (Danio rerio).

Kurzübersicht für Cytokeratin 19 Antikörper (ABIN114673)

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Reaktivität: Human, Zebrafisch (Danio rerio)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: RCK108

Produktdetails anti-Cytokeratin 19 Antikörper

Spezifität: Clone RCK108 specifically reacts with Cytokeratin 19, found in most glandular simple type epithelia and most carcinomas. Does not react with hepatocytes and hepatocellular carcinoma.

Aufreinigung: Purified

Immunogen: Cytoskeletal preparation of Human bladder carcinoma cell line T24

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry- on frozen sections. - on paraffin embedded tissues (pre-treatment with pepsin or trypsin). Immunocytochemistry. Immunoblotting. Flow cytometry: 1: 100 - 1: 1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in alqiuots) at -20 °C for longer.

Details zu Cytokeratin 19

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Andere Bezeichnung: Cytokeratin 19

Hintergrund: Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.Individual human cytokeratins are numbered 1 to 20.Synonyms: CK19, Cytokeratin-19, K19, KRT19, Keratin type I cytoskeletal 19, Keratin-19

Gen-ID: 3880

NCBI Accession: NP_002267

UniProt: P08727